According to the 2004 UNAIDS Report on the Global AIDS Epidemic, it is estimated that 29% of Lesotho between the age of 15 and 49 are infected with HIV & AIDS, making Lesotho the country with the third highest prevalence in the world. How can we, as democratically elected Parliamentarians and leaders of the country, support the National Strategies developed for Scaling Up the National Response to the HIV & AIDS pandemic in Lesotho, and work toward the goal of being able to manage and revert the epidemic? This document offers guidelines to increase the involvement and the efficiency of parliamentarians with respect to HIV/AIDS prevention and managements.